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WDFY4 Antibody, Biotin conjugated

Datasheet
Code CSB-PA747798LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) WDFY4 Polyclonal antibody
Uniprot No.
Q6ZS81
Target Names
WDFY4
Alternative Names
WDFY4 antibody; C10orf64 antibody; KIAA1607WD repeat- and FYVE domain-containing protein 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human WD repeat- and FYVE domain-containing protein 4 protein (1-322AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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WDFY4 Antibodies

WDFY4 Proteins

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Target Background

Function
Plays a critical role in the regulation of cDC1-mediated cross-presentation of viral and tumor antigens in dendritic cells. Mechanistically, acts near the plasma membrane and interacts with endosomal membranes to promote endosomal-to-cytosol antigen trafficking. Plays also a role in B-cell survival through regulation of autophagy.
Gene References into Functions
  1. A significantly increased risk for RA associated with the WDFY4 rs7097397 AG genotype. PMID: 24549174
  2. rs877819 SNP in WDFY4 may be associated with systemic lupus erythematosus by reduced binding of YY1 and downregulating WDFY4 expression. PMID: 22972472
  3. Genetic variants in ETS1 and WDFY4 were found to be associated with systemic lupus erythematosus, in the Asian population studied. PMID: 20169177
Subcellular Location
Early endosome. Endoplasmic reticulum.
Database Links

HGNC: 29323

OMIM: 613316

KEGG: hsa:57705

STRING: 9606.ENSP00000320563

UniGene: Hs.287379

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